As for Carnage himself, I've been thinking in terms of the video game storyline vs. the comic plot. I honestly think the video game incarnation of Carnage was the first one (its Peter really, but if you've played the game you know what I mean). The reason I say this is in regards to the Carnage arc in the comic, it makes more sense that way, especially in terms of the timeline. Assuming the Peter-Carnage version was the first, it makes more sense for Dr. Connors to be able to grow the second Carnage in his lab, given that it might have imprinted itself somehow on Peter's DNA as a result of the events in the video game. Of course in the game it was due to the Venom particles in Peter's blood, but in the Carnage arc Connors mentions he grew the second Carnage in his lab by combining Peter's blood with Peter's father's work...in other words, the Venom formula. And voila, another Carnage. After all, in the videogame the first Carnage was created due to a combination of the Venom stuff in his blood, and whatever it was Toomes injected into Peter. And since Bendis himself says the game takes place after the Geldoff arc (he specifically said after #45), it makes sense. This theory is also backed up reconciling the events of both the videogame and comics. Just figured I'd share that.