Well here's a few thoughts ...
1) We're given a hint about what makes people responsive to the super soldier serum. Both Captain America and Abdul were sickly (of some sort) before they got it, and I'd bet most everyone that got it in between were pretty tough soldiers allready. So I'd assume that they share some sort of disease that is needed in order to be responsive to the super soldier serum, or maybe you just need to be a weakling in order for it to have enough unused potential to work with.
2) Fingernails ... you know what, I'll just pretend that never happened. There's a few redeeming things about it but ... It doesn't say he kills the people there. In fact, it seems more like he did something to their nerve system or so, so either they can't control themself very well or they can't breathe. You see one guy leaning over supporting himself on the wall, so they are clearly not instantly dead. I would be inclined to suspend my disbelief if they weren't wearing masks covering the head and the neck, which the fingernails couldn't possibly penetrate.
There's degrees of realism in books, movies, comics etc. Basically, you are given a scenario, you are given enough information to get an idea as to how the universe works in the scenario you are reading about / watching, and as to how much realism matters. Taking a few examples, I'd say winnie the poh, donald duck, simpsons, Lucifer, Hellblazer and the ultimates all have varying degrees of realism in their universes. Given the Ultimate Universe so far, physics definitively seems to be working somewhat similiar to the real world, and having fingernails disregard air resistance and penetration power needed to get through those ski masks is just bleh. Stupid.
3) Tony Stark rocks. Go go Iron Man, and I bet this is quite a nasty bit of work, probably something that never has been used before because it's too much overkill for the "normal" work.
4) Wasp is good. Cap America is ... too predictable. Didn't like his one line in the issue.
5) I think that Fury has had Plym working as a double agent. There's a few interesting things that point in that direction. One, he is really annoyed he wasn't told about the invasion and the massive destruction etc. He didn't know the scale of what was planned. Which would explain why Fury is taken by surprise as well, since he could have known about it, but not known all the details or the timing and therefore been surprised as well. Especially if he "thought" he knew everything from an inside source (Plym).
Also, there's just so many possible double meanings to what he says when he is asked if his robots can keep the peace, hehe. Besides, when Wasp was meeting him outside in an earlier issue, I remember him not wanting to talk about what he was doing at the time + saying he was brave "behind everyones back", which could have a few double meanings as well if he turns out to actually be a hero. He might have been given one last chance by Fury to redeem himself... well, it's a theory at least.
6) I liked it, altho it was mostly just a "setup" issue. I'll give it 4/5.
7) I hope we'll see Hulk, Thor and Iron Man kick some major *** later on
. An intelligent improved Hulk (result from the wolverine vs thor crossover), an Iron Man with a suit he never had to use before, and a really pissed Thor ... well that ought to do it
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