Here's my cast
Emma Frost: Charlize Theron
I think she looks and fits the part. She's smart, sassy and attractive and has that thing about her that just completely fits Emma.
Cyclops: Brad Pitt
He is good looking and can easily play a self-righteous douche who can be the fearless leader in the face of adversity. Pitt's my pick and he's around the same age as theron making it believable as a couple.
Kitty Pryde: Natalie Portman
This one was easily castable. Kitty is small. Portman is small. Both are simple people that can become complex and deep in character when the situation calls for it. Portman also has the looks and feature to play kitty.
Wolverine: Thomas Jane
He's played the unrelatable gung ho anti-hero before, and he's only interested in those types and I think he fits the bill for wolverine. He can be the scruffy, tough on the outside but chewy on the inside character that is wolverine and i just don't see anyone better. I tried finding someone shorter but no one came to mind
Beast: Nick Frost
I love Nick Frost and him being Beast would be the coolest. Even if he doesn't quite fit the physique, he'd play well to wolverines cynism and bring that light heartedness the astonishing has at times. He's accent's a little off too and I'm really stretching the possibility here, but I think given the chance, He'd be a great pick.
Colossus: Robert Maillet
This was the guy who played the huge Immortal in 300, the one who got his head chopped off by Leonidus in the heat of battle. He's massive and the one reason i could think of not casting cheesburger eddie. Shave the beard and give him the clean look and you may have the quiet, kept but massively strong Colossus.
Agent Brand: Jordana Brewster
I'm not too familiar with her movie base but with this picture and her hair the way it is, all you'd have to do is slap on some green hair, big shades and a famas and you've got agent brand.
Danger: Kate Blanchett
i'm thinking danger would be robotronic or cgi in some scenes but for voice, I totally see her doing it?
Ord: Benicio DelTorro
This one just kind of came to me. I think it makes sense though. He can play arrogant. He can play tough and superior and even though his accent might throw it off, I think he'd fit Ord pretty well, green skin and all.